The two, who have been on top form for Ghana, having represented the country in the just-ended World Athletics Championship, battled against seven other top opponents in their respective races.
24-year-old Azamati, who is currently the national 100m record holder, finished first place in heat seven with a time of 10.19 seconds, whiles Safo-Antwi also grabbed the fourth place slot with a time of 10.33 seconds in heat 10.
Having grabbed the top spots, the two would represent Ghana once again in the semi-finals of the 100-metre race which is scheduled for Wednesday, August 3.
Azamati and Safo Antwi are poised to make history as they seek to grab Gold for team Ghana on the international front.
Ghana is yet to grab a medal in this year’s Commonwealth Games after six days.